Massive normalization of olfactory bulb output in mice with a ‘monoclonal nose’

Roland. B., R. Jordan, D.L. Sosulski, A. Diodato, I. Fukunaga, I. Wickersham, K.M. Franks, A.T. Schaefer, A. Fleischmann. Elife 5. pii: e16335 (2016). Perturbations in neural circuits can provide mechanistic understanding of the neural correlates of behavior. In M71 transgenic mice with a “monoclonal nose”, glomerular input patterns in the olfactory bulb are massively perturbed […]

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National Institutes of Health (NIH), NIMH

We will use high throughput techniques to produce a set of viral vectors that will allow selective expression of transgenes in specific populations of neurons in the brain. Along with many other applications, this will allow optogenetic control, recording, and genomic modification of targeted neuronal populations without the need for production of transgenic or knock-out […]

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BRAIN Initiative award: A platform for high-throughput production of targeting systems for cell-type-specific transgene expression in wild-type animals

Ian Wickersham and co-PI Robert Desimone have been awarded a BRAIN Initiative R01 grant for “A platform for high-throughput production of targeting systems for cell-type-specific transgene expression in wild-type animals”. The project will use high throughput techniques to produce a set of viral vectors that will allow selective expression of transgenes in specific populations of […]

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Postdoc Lei Jin joins the lab

Lei Jin has joined the lab as a postdoctoral fellow, with a bachelor’s in Biotechnology from Hainan University, a master’s in Biology from Tsinghua University, and a Ph.D. in Bioelectronics from RWTH Aachen University. He is supported by a fellowship from the Simons Center for the Social Brain.

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